Impact of Molecular Biology in Life Science


Journal of Molecular biology and Biotechnology is a peer reviewed journal that focusses on comprehensive and extensive coverage of research developments in the field of molecular biology and biotechnology. Molecular biology is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions. The field of molecular biology studies macromolecules and the macromolecular mechanisms found in living things, such as the molecular nature of the gene and its mechanisms of gene replication, mutation, and expression. Given the fundamental importance of these macromolecular mechanisms throughout the history of molecular biology, a philosophical focus on the concept of a mechanism generates the clearest picture of molecular biology’s history, concepts, and case studies utilized by philosophers of science. Molecular biology use specific techniques native to molecular biology, but increasingly combine these with techniques and ideas from genetics and biochemistry. Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules such as nucleic acids and proteins that carry out the biological processes essential for the cells functions and maintenance. The field of molecular biology has a profound impact in life science investigation. Major advances in molecular biology over the last four decades have stimulated research and progress in almost all the disciplines of life science. This driving force involves. The development of more and more sophisticated experimental techniques in molecular biology with a broad, interdisciplinary applicability, the ever-expanding flow of information of technical novelties and scientific discoveries across the scientific community and the development of specific software and continuously updated databases for, respectively, analyzing and storing data on genotypes, gene expression levels, cytogenetic profiles and other molecular features. This has changed the rationale and approach of scientific experimentations allowing revolutionizing discoveries not only in molecular biology but also in biochemistry, biophysics, biotechnology, cell biology, and genetics. One major example is the innovation in high-throughput biology, next generation sequencing and recombinant DNA technology, which made possible to unveil the high complexity of the genome and elucidate the precise mechanisms for the transmission of the genetic information. So, it is now proven that gene expression, DNA replication, DNA repair, and sister chromatid segregation are processes much more complicated than previously thought. This complexity includes, but is not limited to, the existence of interconnected regulatory pathways involving also previously unexpected actors, such as non-coding RNAs, the relevance of epigenetic mechanisms and post-transcriptional modifications, the importance of the correct execution, timing, sequentially and coordination of all cell cycle events, the pleiotropic functions of players operating in these processes; and the influence of the energetic metabolisms and environmental signals. Moreover, it has become evident that the deregulation of these molecular processes is associated with, and in certain circumstances is the direct cause of, a wide range of pathological conditions. Although this module is focused on life sciences, it is, however, necessary to mention the biomedical relevance of molecular biology-related investigations for drug discovery and the development of a more personalized medicine. Given the rapidly changing and continuously evolving nature of the molecular biology field, we can anticipate that the revolutionary impact of molecular biology in life sciences is only at the beginning and is far from being finished. Steven Edwards Associate Editor  Journal of Molecular Biology and Biotechnology 

Steven Edwards 
Associate Editor
Journal of Molecular Biology and Biotechnology